COTL1 antibody

Category: Research Area:
Synonyms：Coactosin-like protein|COTL1|CLP antibody
Catalogue No.：FNab01888Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
COTL1 antibody
Catalogue No.
FNab01888
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
coactosin-like 1
Alternative Names
Coactosin-like protein|COTL1|CLP antibody
UniProt ID
Q14019
Observed MW
14 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01888(COTL1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab01888(COTL1 antibody) at dilution of 1:50
Background
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
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