DDIT3 antibody

Synonyms:DNA damage-inducible transcript 3 protein (DDIT-3)|C/EBP zeta|C/EBP-homologous protein (CHOP)|C/EBP-homologous protein 10 (CHOP-10)|CCAAT/enhancer-binding protein homologous protein|Growth arrest and DNA damage-inducible protein GADD153|DDIT3|CHOP|CHOP10|GADD153 antibody
Catalogue No.:FNab01668Reactivity:Human, Mouse, Rat
Host:MouseTested Application:ELISA, WB
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
DDIT3 antibody
Catalogue No.
FNab01668
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
5H7
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
DNA-damage-inducible transcript 3
Alternative Names
DNA damage-inducible transcript 3 protein (DDIT-3)|C/EBP zeta|C/EBP-homologous protein (CHOP)|C/EBP-homologous protein 10 (CHOP-10)|CCAAT/enhancer-binding protein homologous protein|Growth arrest and DNA damage-inducible protein GADD153|DDIT3|CHOP|CHOP10|GADD153 antibody
UniProt ID
P35638
Observed MW
30 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:5000
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab01668(CHOP Antibody) at dilution of 1:1000
Background
CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.