Products
CHAT antibody
- Product Name
- CHAT antibody
- Catalogue No.
- FNab01631
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- choline acetyltransferase
- Alternative Names
- Choline O-acetyltransferase (CHOACTase antibody, ChAT antibody, Choline acetylase)|CHAT antibody
- UniProt ID
- P28329
- Observed MW
- 68 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab01631( CHAT Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab01631( CHAT Antibody) at dilution of 1:200
- Background
- This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
