Products
CD59 antibody
- Product Name
- CD59 antibody
- Catalogue No.
- FNab01489
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD59 molecule, complement regulatory protein
- Alternative Names
- MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MSK21 antibody
- UniProt ID
- P13987
- Observed MW
- 18-20 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab01489(CD59 antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab01489(CD59 antibody) at dilution of 1:100
- Background
- Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
