Products
CD47 antibody
- Product Name
- CD47 antibody
- Catalogue No.
- FNab01486
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD47 molecule
- Alternative Names
- CD47 antibody, CD47 molecule antibody, IAP antibody, Leukocyte surface antigen CD47 antibody, MER6 antibody, OA3 antibody, Protein MER6 antibody
- UniProt ID
- Q08722
- Observed MW
- 47-55 kDa
Application
- Tested Applications
- ELISA, WB,IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:50-1:500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01486(CD47 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab01486(CD47 Antibody) at dilution of 1:200
- Background
- Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus(By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
