Products
BUB1 antibody
- Product Name
- BUB1 antibody
- Catalogue No.
- FNab00987
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- budding uninhibited by benzimidazoles 1 homolog (yeast)
- Alternative Names
- Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1)|BUB1A|BUB1|BUB1L antibody
- UniProt ID
- O43683
- Observed MW
- 133 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab00987( BUB1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat liver using FNab00987(BUB1 antibody) at dilution of 1:100
- Background
- This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
