Products
BTK antibody
- Product Name
- BTK antibody
- Catalogue No.
- FNab00980
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Bruton agammaglobulinemia tyrosine kinase
- Alternative Names
- Tyrosine-protein kinase BTK|Agammaglobulinemia tyrosine kinase (ATK)|B-cell progenitor kinase (BPK)|Bruton tyrosine kinase|BTK|AGMX1|ATK|BPK antibody
- UniProt ID
- Q06187
- Observed MW
- 70-76 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab00980(BTK antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded rat spleen using FNab00980(BTK antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab00980(BTK antibody) at dilution of 1:50
- Background
- The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
