anti- BMP15 antibody
FNab00916
Catalogue No.
- Synonyms:
- GDF9B
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC, IF
Product Information
- Product Name
- anti- BMP15 antibody
- Catalogue No.
- FNab00916
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9) . This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.
Immunogen Information
- Immunogen
- bone morphogenetic protein 15
- Synonyms
- GDF9B
- Observed MW
- 45 kDa
Application
- Tested Application
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Uniprot information
- UniProt ID
- O95972
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded human kidney using FNab00916 (BMP15 Antibody) at dilution of 1:50
- Image 4
-
A2780 cells were subjected to SDS PAGE followed by western blot with FNab00916 (BMP15 antibody) at dilution of 1:1000