HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00892(BID antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab00892(BID antibody) at dilution of 1:100
Background
The major proteolytic product p15 BID allows the release of cytochrome c(By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.