Products
BATF2 antibody
- Product Name
- BATF2 antibody
- Catalogue No.
- FNab00808
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- basic leucine zipper transcription factor, ATF-like 2
- Alternative Names
- B ATF 2 antibody, BATF2 antibody, basic leucine zipper transcription factor antibody, ATF-like 2 antibody
- UniProt ID
- Q8N1L9
- Observed MW
- 29 kDa
Application
- Tested Applications
- ELISAA, WB, IP
- Recommended dilution
- WB: 1:200-1:1000; IP: 1:200-1:1000
Validated Images
IP Result of anti-BATF2 (IP:FNab00808, 3ug; Detection:FNab00808 1:300) with HeLa cells lysate 1200ug.
- Background
- AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes(By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
