Products

BACE2 antibody

Synonyms:AEPLC antibody, ALP56 antibody, ASP21 antibody
Catalogue No.:FNab00782Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BACE2 antibody
Catalogue No.
FNab00782
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
beta-site APP-cleaving enzyme 2
Alternative Names
AEPLC antibody, ALP56 antibody, ASP21 antibody
UniProt ID
Q9Y5Z0
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00782(BACE2 antibody) at dilution of 1:500
Background
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.