mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00700( ATP2C1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab00700(ATP2C1 antibody) at dilution of 1:100
Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.