Products
ARFGAP1 antibody
- Product Name
- ARFGAP1 antibody
- Catalogue No.
- FNab00536
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ADP-ribosylation factor GTPase activating protein 1
- Alternative Names
- ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1)|ADP-ribosylation factor 1 GTPase-activating protein (ARF1 GAP)|ARF1-directed GTPase-activating protein|ARFGAP1|ARF1GAP antibody
- UniProt ID
- Q8N6T3
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab00536(ARFGAP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab00536(ARFGAP1 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
