human blood tissue were subjected to SDS PAGE followed by western blot with FNab00317(SERPINA3, AACT antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab00317( SERPINA3, AACT Antibody) at dilution of 1:50
Background
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.