Products
ALDH4A1 antibody
- Product Name
- ALDH4A1 antibody
- Catalogue No.
- FNab00296
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aldehyde dehydrogenase 4 family, member A1
- Alternative Names
- Delta-1-pyrroline-5-carboxylate dehydrogenase antibody, mitochondrial (P5C dehydrogenase)|Aldehyde dehydrogenase family 4 member A1|L-glutamate gamma-semialdehyde dehydrogenase|ALDH4A1|ALDH4|P5CDH antibody
- UniProt ID
- P30038
- Observed MW
- 61 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab00296(ALDH4A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab00296(ALDH4A1 antibody) at dilution of 1:100
- Background
- This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
