human heart tissue were subjected to SDS PAGE followed by western blot with FNab00243(AK1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab00243(AK1 antibody) at dilution of 1:100
Background
This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.