Products
ADCY6 antibody
- Product Name
- ADCY6 antibody
- Catalogue No.
- FNab00157
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- adenylate cyclase 6
- Alternative Names
- AC6 antibody, ADCY6 antibody, adenylate cyclase 6 antibody, Adenylate cyclase type 6 antibody, Adenylate cyclase type VI antibody, Adenylyl cyclase 6 antibody, ATP pyrophosphate lyase 6 antibody, DKFZp779F075 antibody, KIAA0422 antibody
- UniProt ID
- O43306
- Observed MW
- 131 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:200-1:2000; IP: 1:200-1:1000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab00157(ADCY6 antibody) at dilution of 1:200
IP Result of anti-ADCY6 (IP:FNab00157, 4ug; Detection:FNab00157 1:300) with mouse brain tissue lysate 4000ug.
- Background
- Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).
