mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab00064(ACADL-Specific antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab00064(ACADL-Specific Antibody) at dilution of 1:50
Background
ACADL(Long-chain specific acyl-CoA dehydrogenase, mitochondrial) is also named as LCAD and belongs to the acyl-CoA dehydrogenase family.It catalyzes the first reaction of the mitochondrial β-oxidation of fatty acids and is synthesized in the cytosol as a precursor that is larger than its mature from. The size difference between the precursor and mature rat LCAD has been estimated to be 3 kDa on the basis of SDS-PAGE(PMID:1774065).Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency(ACADVLD).