Products

anti- 15 Lipoxygenase 2 antibody

FNab00005 Catalogue No.
Synonyms:
ALOX15B;Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-LOX-2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-Lob
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Isotype:
IgG
Tested Application:
ELISA, WB, IHC, IF
Product Information
Product Name
anti- 15 Lipoxygenase 2 antibody
Catalogue No.
FNab00005
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating (ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes (ALOX15, ALOX15B) . ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms. (PMID:24373925) . ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.
Immunogen Information
Immunogen
arachidonate 15-lipoxygenase, type B
Synonyms
ALOX15B;Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-LOX-2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-Lob
Observed MW
76 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Uniprot information
UniProt ID
O15296
Images
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab00005 (ALOX15B antibody) at dilution of 1:100
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00005 (ALOX15B antibody) at dilution of 1:600