Various lysates were subjected to SDS PAGE followed by western blot with FNab10741(LPP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab10741(LPP antibody) at dilution of 1:100
Background
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.