Products
CD79A antibody
- Product Name
- CD79A antibody
- Catalogue No.
- FNab10737
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD79a molecule, immunoglobulin-associated alpha
- Alternative Names
- CD79A antibody, Ig alpha antibody, IGA antibody, MB 1 antibody, MB 1 membrane glycoprotein antibody, MB1 antibody, Surface IgM associated protein antibody
- UniProt ID
- P11912
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Mouse spleen were subjected to SDS PAGE followed by western blot with FNab10737(CD79A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat spleen tissue slide using FNab10737(CD79A antibody) at dilution of 1:100
- Background
- Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
