Products
HAX1 antibody
- Product Name
- HAX1 antibody
- Catalogue No.
- FNab10721
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- HCLS1 associated protein X-1
- Alternative Names
- FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX1 antibody, HCLS1 associated protein X 1 antibody, HCLSBP1 antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1BP1 antibody, HSP1BP 1 antibody, SCN3 antibody
- UniProt ID
- O00165
- Observed MW
- 31 kDa, 36 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
MCF-7 cell lysates were subjected to SDS PAGE followed by western blot with FNab10721(HAX1 antibody) at dilution of 1:1000
- Background
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
