Products
LILRB4 antibody
- Product Name
- LILRB4 antibody
- Catalogue No.
- FNab10516
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Leukocyte immunoglobulin-like receptor subfamily B member 4
- Alternative Names
- LILRB4 antibody, CD85K antibody, ILT-3 antibody, ILT3 antibody, LIR-5 antibody, LIR5 antibody
- UniProt ID
- Q8NHJ6
- Observed MW
- 49 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab10516(LILRB4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab10516(LILRB4 antibody) at dilution of 1:50
- Background
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
