LOXL2 antibody

Synonyms:LOXL2 antibody, LOR antibody, LOR2 antibody, WS9-14 antibody
Catalogue No.:FNab10512Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
LOXL2 antibody
Catalogue No.
FNab10512
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Lysyl oxidase homolog 2
Alternative Names
LOXL2 antibody, LOR antibody, LOR2 antibody, WS9-14 antibody
UniProt ID
Q9Y4K0
Observed MW
87-100 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
Mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab10512(LOXL2 antibody) at dilution of 1:1000
Background
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.