GSK3B antibody

Catalogue No.:FNab10503Reactivity:Human, Rat
Host:MouseTested Application:ELISA, WB, IHC, IF
Clonality:monoclonalIsotype:IgG1
  • SPECIFICATIONS
Product Name
GSK3B antibody
Catalogue No.
FNab10503
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
5F4
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glycogen synthase kinase 3 beta
UniProt ID
P49841
Observed MW
47 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10503(GSK3B antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab10503( GSK3B Antibody) at dilution of 1:100
Immunofluorescent analysis of Hela cells using FNab10503(GSK3B antibody) at dilution of 1:50.
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.