Products
TLR2 antibody
- Product Name
- TLR2 antibody
- Catalogue No.
- FNab10498
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Toll-like receptor 2
- Alternative Names
- CD282 antibody, TIL4 antibody, TLR2 antibody
- UniProt ID
- O60603
- Observed MW
- 105 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
Rat spleen tissue were subjected to SDS PAGE followed by western blot with FNab10498(TLR2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Rat spleen tissue slide using FNab10498(TLR2 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
