Products
KNG1 antibody
- Product Name
- KNG1 antibody
- Catalogue No.
- FNab10493
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Kininogen-1
- Alternative Names
- KNG1 antibody, BDK antibody, BK antibody, KNG antibody
- UniProt ID
- P01042
- Observed MW
- 68 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:50-1:200
Validated Images
HT-29 cells were subjected to SDS PAGE followed by western blot with FNab10493(KNG1 antibody) at dilution of 1:1000
Immunofluorescent analysis of L929 cells using FNab10493(KNG1 antibody) at dilution of 1:50.
- Background
- This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
