Products
GRP78/BIP antibody
- Product Name
- GRP78/BIP antibody
- Catalogue No.
- FNab10492
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 3F8
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Endoplasmic reticulum chaperone BiP
- Alternative Names
- HSPA5 antibody, BIP antibody, GRP78 antibody, HEL-S-89n antibody, MIF2 antibody
- UniProt ID
- P11021
- Observed MW
- 70-78 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10492(GRP78/BIP antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab10492(GRP78/BIP antibody) at dilution of 1:50
- Background
- GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.
