Products
YTHDC2 antibody
- Product Name
- YTHDC2 antibody
- Catalogue No.
- FNab10487
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- 3'-5' RNA helicase YTHDC2
- Alternative Names
- YTHDC2 antibody, CAHL antibody
- UniProt ID
- Q9H6S0
- Observed MW
- 160 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:50-1:200
Validated Images
rat testis tissue were subjected to SDS PAGE followed by western blot with FNab10487(YTHDC2 antibody) at dilution of 1:1000
Immunofluorescent analysis of NIH/3T3 cells using FNab10487(YTHDC2 antibody) at dilution of 1:50.
- Background
- This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
