Products
SP1 antibody
- Product Name
- SP1 antibody
- Catalogue No.
- FNab10486
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Transcription factor Sp1
- Alternative Names
- SP1 antibody
- UniProt ID
- P08047
- Observed MW
- 90 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab10486(SP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat liver tissue slide using FNab10486(SP1 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
