mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab10473(TSPO antibody) at dilution of 1:1000
Immunofluorescent analysis of L929 cells using FNab10473(TSPO antibody) at dilution of 1:50.
Background
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.