PCSK4 antibody

Synonyms:PC4 antibody, PCSK4 antibody, Proprotein convertase 4 antibody, SPC5 antibody
Catalogue No.:FNab10362Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PCSK4 antibody
Catalogue No.
FNab10362
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
proprotein convertase subtilisin/kexin type 4
Alternative Names
PC4 antibody, PCSK4 antibody, Proprotein convertase 4 antibody, SPC5 antibody
UniProt ID
Q6UW60
Observed MW
26 kDa, 72 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10362(PCSK4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10362(PCSK4 antibody) at dilution of 1:100
Background
Proprotein convertase subtilysin/Kexin Type4 (PCSK4) is a protein convertase enzymes in spermatozoa acrosome membrane, it has an important role in the acrosome reaction through endoproteolytic process that converts the precursor proteins into bioactive protein as a necessary substance to penetrate on the zona pellucida (PMID: 16040806 ). The molecular mass of pro-PCSK4 is 72kDa, and mature PCSK4 is 54 kDa (PMID: 16040806, 19109312).