Hela cells were subjected to SDS PAGE followed by western blot with FNab10338(SGK1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab10338( SGK1 Antibody) at dilution of 1:100
Background
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.