Immunohistochemistry of paraffin-embedded human colon cancer using FNab10111(GIF antibody) at dilution of 1:200
Background
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.