Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10078(P2RX7 Antibody) at dilution of 1:200
Background
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.