rat brain were subjected to SDS PAGE followed by western blot with FNab10075(TRAF5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab10075(TRAF5 antibody) at dilution of 1:100
Background
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.