LO2 cells were subjected to SDS PAGE followed by western blot with FNab10069(NCOR2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung using FNab10069( NCOR2 Antibody) at dilution of 1:100
Background
Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.