PIK3R1 antibody

Synonyms:AGM7 antibody, GRB1 antibody, IMD36 antibody, p85 antibody, p85-ALPHA antibody
Catalogue No.:FNab09963Reactivity:Human, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PIK3R1 antibody
Catalogue No.
FNab09963
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
PIK3R1
Alternative Names
AGM7 antibody, GRB1 antibody, IMD36 antibody, p85 antibody, p85-ALPHA antibody
UniProt ID
P27986
Observed MW
95kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
THP-1 cells were subjected to SDS PAGE followed by western blot with FNab09963(PIK3R1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab09963(PIK3R1 Antibody) at dilution of 1:100
Background
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.