Products
USP7 antibody
- Product Name
- USP7 antibody
- Catalogue No.
- FNab09960
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 7
- Alternative Names
- HAUSP antibody, TEF1 antibody
- UniProt ID
- Q93009
- Observed MW
- 130 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09960(USP7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney cancer slide using FNab09960(USP7 Antibody) at dilution of 1:100
- Background
- The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
