A431 cells were subjected to SDS PAGE followed by western blot with FNab09947(CREB1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab09947(CREB1 Antibody) at dilution of 1:100
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element(CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.