Products
Caspase 2 antibody
- Product Name
- Caspase 2 antibody
- Catalogue No.
- FNab098281
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 2B10
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Caspase 2
- Alternative Names
- CASP 2 antibody, CASP2 antibody, Caspase 2 antibody, Caspase2 antibody, ICH 1L antibody, ICH 1L/1S antibody, ICH1 antibody, NEDD 2 antibody, NEDD2 antibody, Protease ICH 1 antibody
- UniProt ID
- P42575
- Observed MW
- 18, 32, 50 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:1000-1:6000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab098281 (Caspase 2 antibody) at dilution of 1:3000
- Background
- CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.
