HeLa cells were subjected to SDS PAGE followed by western blot with FNab09827( YAP1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab09827(YAP1 antibody) at dilution of 1:100
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.