Products
P Glycoprotein antibody
- Product Name
- P Glycoprotein antibody
- Catalogue No.
- FNab09805
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ABCB1
- Alternative Names
- ABCB1 antibody, CD243 antibody, GP170 antibody, MDR1 antibody, Multidrug resistance protein 1 antibody, P glycoprotein 1 antibody
- UniProt ID
- P08183
- Observed MW
- 142 kDa
Application
- Tested Applications
- ELISA, WB, IP, IHC
- Recommended dilution
- WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
Validated Images
unboiled HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09805(P glycoprotein antibody) at dilution of 1:300
IP Result of anti-P glycoprotein (IP: FNab09805, 4ug; Detection: FNab09805 1:300) with human placenta tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09805(P glycoprotein antibody) at dilution of 1:500
- Background
- ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
