Products
Vinculin antibody
- Product Name
- Vinculin antibody
- Catalogue No.
- FNab09799
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vinculin
- Alternative Names
- CMD1W antibody, Metavinculin antibody, MVCL antibody, VCL antibody, Vinculin antibody
- UniProt ID
- P18206
- Observed MW
- 124 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09799(Vinculin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using FNab09799( Vinculin Antibody) at dilution of 1:100
- Background
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
