Products
ZKSCAN3 antibody
- Product Name
- ZKSCAN3 antibody
- Catalogue No.
- FNab09646
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- zinc finger with KRAB and SCAN domains 3
- Alternative Names
- ZKSCAN3 antibody, dJ874C20.1 antibody, KIAA0426 antibody, ZF47 antibody, ZFP306 antibody
- UniProt ID
- Q9BRR0
- Observed MW
- 62 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09646(ZKSCAN3 antibody) at dilution of 1:500
- Background
- Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
