Products
ZC3H8 antibody
- Product Name
- ZC3H8 antibody
- Catalogue No.
- FNab09605
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- zinc finger CCCH-type containing 8
- Alternative Names
- Fliz1 antibody, ZC3H8 antibody, ZC3HDC8 antibody
- UniProt ID
- Q8N5P1
- Observed MW
- 34 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:1000-1:10000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab09605(ZC3H8 Antibody) at dilution of 1:2000
- Background
- Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region(IRR) of the GATA3 gene(By similarity). Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
