Products
YME1L1 antibody
- Product Name
- YME1L1 antibody
- Catalogue No.
- FNab09566
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- YME1-like 1
- Alternative Names
- FTSH antibody, FTSH1 antibody, Meg 4 antibody, MEG4 antibody, PAMP antibody, YME1 like 1 antibody, YME1 like protein 1 antibody, YME1L antibody, YME1L1 antibody
- UniProt ID
- Q96TA2
- Observed MW
- 86 kDa, 60 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab09566(YME1L1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09566(YME1L1 antibody) at dilution of 1:100
- Background
- YME1L1(ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L,Meg-4,PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa.
