anti- XRCC5/Ku80 antibody
FNab09555
Catalogue No.
- Synonyms:
- 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22P2, KARP 1, KARP1, Ku80, Ku86, KUB2, NFIV, Nuclear factor IV, Thyroid lupus autoantigen, TLAA, XRCC5
- Host:
- Rabbit
- Reactivity:
- Human
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC
Product Information
- Product Name
- anti- XRCC5/Ku80 antibody
- Catalogue No.
- FNab09555
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Immunogen Information
- Immunogen
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- Synonyms
- 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22P2, KARP 1, KARP1, Ku80, Ku86, KUB2, NFIV, Nuclear factor IV, Thyroid lupus autoantigen, TLAA, XRCC5
- Observed MW
- Refer to figures
Application
- Tested Application
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
- UniProt ID
- P13010
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09555 (XRCC5 antibody) at dilution of 1:100
- Image 4
-
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09555 (XRCC5 antibody) at dilution of 1:1000