Products
XRCC5 antibody
- Product Name
- XRCC5 antibody
- Catalogue No.
- FNab09555
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- Alternative Names
- X-ray repair cross-complementing protein 5|86 kDa subunit of Ku antigen|ATP-dependent DNA helicase 2 subunit 2|ATP-dependent DNA helicase II 80 kDa subunit|CTC box-binding factor 85 kDa subunit (CTC85 antibody, CTCBF)|DNA repair protein XRCC5|Ku80|Ku86|Lupus Ku autoantigen protein p86|Nuclear factor IV|Thyroid-lupus autoantigen (TLAA)|X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)|XRCC5|G22P2 antibody
- UniProt ID
- P13010
- Observed MW
- 83kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09555(XRCC5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09555(XRCC5 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
