Products
XRCC4 antibody
- Product Name
- XRCC4 antibody
- Catalogue No.
- FNab09554
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- X-ray repair complementing defective repair in Chinese hamster cells 4
- Alternative Names
- DNA repair protein XRCC4 (hXRCC4)|X-ray repair cross-complementing protein 4|Protein XRCC4 antibody, C-terminus (XRCC4/C)|XRCC4 antibody
- UniProt ID
- Q13426
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab09554(XRCC4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09554(XRCC4 antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab09554(XRCC4 antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.
- Background
- The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
