Various lysates were subjected to SDS PAGE followed by western blot with FNab09519(WNT3A antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human lung cancer using FNab09519(WNT3A antibody) at dilution of 1:100
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.